Journal Publications / Patents / Book Chapters
- Hasan Zümrüt, Naznin Ara, George Maio, Nabeela Van, Sana Battol and Prabodhika Mallikaratchy “Ligand-guided selection of aptamers against T-cell Receptor-cluster of differentiation 3 (TCR-CD3) expressed on Jurkat.E6 cells” Submitted 2016.
- Hasan Zümrüt, Naznin Ara, Maria Fraile, George Maio, Prabodhika Mallikaratchy “Ligand-Guided Selection of Target-Specific Aptamers: A Screening Technology for Identifying Specific Aptamers Against Cell-Surface Proteins”. Nucleic Acid Ther. 2016 Jun;26(3):190-8. doi: 10.1089/nat.2016.0611. Epub 2016 May 5
- US Patent application: 15/097, 845, “LIGAND-GUIDED-SELECTION METHOD FOR SCREENING ANTIGEN SPECIFIC LIGANDS”
- Prabodhika Mallikaratchy, Zumrut, Hasan, Ara, Naznin “Discovery of Biomarkers Using Aptamers Evolved in Cell-SELEX Method”, Aptamers selected by cell-SELEX for Theranostics” Principles, Eds. W. Tan and X. Fan, SpringerLink. 2015; p.265.
- Prabodhika R. Mallikaratchy, Jeffrey R. Gardner, Lars Ulrik R. Nordstrøm, Nickolas J. Veomett, Michael R. McDevitt, Mark L. Heaney and David A. Scheinberg. “A self-assembling short oligonucleotide duplex for use in vivo” Nucleic Acids Therapeutics, Volume: 23 Issue 4: July 31, 2013.
- US Patent: 13/510,221, Mallikaratchy, Prabodhika, and Scheinberg David, COMPOSITIONS AND METHODS FOR TREATING CANCER AND OTHER DISEASES
- Prabodhika R. Mallikaratchy, Alessandro Ruggiero, Jeffrey R. Gardner, Vitaly Kuryavyi, William F. Maguire, Mark L. Heaney, Michael R. McDevitt, Dinshaw J. Patel and David A. Scheinberg. “A multivalent DNA aptamer specific for the B cell receptor on human lymphoma and leukemia” Nucleic Acids Res. . 2011; 39(6): 2458
- Tang Z., Zhu Z., Mallikaratchy P., Yang R., Sefah K., Tan W. “Aptamer-target binding triggered molecular mediation of singlet oxygen generation” Chem. Asian J. 2010; 5 (4): 783.
- Mallikaratchy P., Liu H., Huang Y.-F., Wang H., Lopez-Colon D. and Tan W. “Using aptamers evolved from cell-SELEX to engineer a drug delivery platform” Chem. Commun. 2009; 7 (21): 3056.
- Mallikaratchy P. and Tang Z., Tan W. “Aptamers evolved from whole cell selection as a selective anti-tumor photodynamic agent”ChemMedChem. 2008; 3 (3): 425.
- Tang Z., Mallikaratchy P., Yang R., Kim Y., Zhu Z., Wang H. and Tan W. “Aptamer switch probe based on intramolecular displacement” J. Am. Chem. Soc. 2008; 130 (34): 11268.
- Shangguan D., Meng L., Mallikaratchy P., Li Y. and Tan, W. “Cell-specific aptamer probes directing cancer biomarker discovery in cancer cells” J. Proteomic Res. 2008; 7 (5): 2133.
- Mallikaratchy P., Tang Z., Kwame S., Meng L., Shangguan D., and Tan W. “Aptamer directly evolved from live cells recognize membrane bound immunoglobin heavy mu chain on Burkitt’s lymphoma cells” Mol. Cell. Proteomics. 2007; 6 (12): 2230.
- Mallikaratchy P., Chen H., Tang Z., Meng L., Shangguan D., Parekh P., Kim Y., Sefah, K., and Tan W. “DNA aptamers for molecular imaging and profiling of cancer”, American Pharm. Rev. 2007; 10 (6): 134.
- Tang Z., Shangguan D., Wang K., Kwame S., Mallikaratchy P., Li, Y., and Tan, W. “Selection of aptamers for molecular recognition and characterization of cancer cells” Anal. Chem. 2007; 79 (13): 4900.
- Shangguan, D., Tang, Z., Mallikaratchy P., Xiao Z., Tan W. “Optimizations and modifications of aptamers selected from live cancer cells”ChemBioChem. 2007; 8 (6): 603.
- H. Chen, Y. Kim, M. O’Donoghue, P. Mallikaratchy, J. Martin, Z. Tang, D. Shangguan, and W. Tan, “Fluorescent Aptamer Probes”, Functional Nucleic Acid Sensors Based on Different Transduction Principles, Eds. Yi Lu and Yingfu Li, SpringerLink. 2007; p.111.
- Shangguan D., Li Y., Tang Z., Cao Z., Chen H., Mallikaratchy P., Kwame S., Yang C. J., and Tan W. “Aptamers evolved from live cells as effective molecular probes for cancer study” Proc. of Natl. Acad. of Sci USA. 2006; 103: 11838.
- Mallikaratchy P., Stahelin R., Cao Z., Cho W., and Tan W. “Combinatorial selection and binding of high affinity DNA ligands targeting protein kinase C delta” Chem. Comm. 2006; 30: 3229.
- W. Tan, Z. Cao, D. Shangguan, Y. Li, Z. Tang, P. Mallikaratchy and H. Chen. “Cancer cell proteomics using molecular aptamers”, Drug Discovery Handbook, Ed. Shayne Cox Gad, Wiley-Inter science, 2005; p. 73.
- Mallikarachy P., Fronczek F. R., Brotherton H. O., and Junk T. “Facile Access to novel organotellurium heterocycles by nitration of Bis- (3, 5-Dimethylphenyl) Ditelluride” J. Het. Chem. 2005; 42 (2): 243.
- Mallikaratchy P., Norman R. E., Fronczek F. R., and Junk T. “Diazenediyldiphenyl-2C2′, N1)-bis [(3,5-dimethyl-phenyl) tellurium(II)]” Acta. Crystallographica. 2005; E61 (7): m1370.
- Mallikaratchy P., Norman R. E., Fronczek F. R., and Junk T. “Tribromo(3,5-dimethyl-2-nitrophenyl-κ2C1,O)tellurium(IV),-bromo(3,5-dimethyl-2-nitrophenyl-κ2C1,O)-tellurium-(II) and bromo(3,5-dimethyl-nitroso-phenyl- κ2 C1,O) tellurium(II)” Acta Crystallographica. 2003; C59: o571.
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