Ligand Guided Selection (LIGS) with Artificially Expanded Genetic Information Systems against TCR-CD3ε
/0 Comments/in Journals, Publications /by malli-adminDiscovery of artificial nucleic acid ligands against cell surface targets
/0 Comments/in Journals, Publications /by malli-adminIntegrating Ligand-Receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands
/0 Comments/in Journals, Publications /by Prabodhika MallikaratchyHasan Zumrut, Sana Batool, Kimon Argyropoulos, Nicole Williams, Roksana Azard, and Prabodhika Mallikaratchy* “Integrating Ligand-receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands” Mol Ther Nucleic Acids. 2019 Sep 6;17:150-163. doi: 10.1016/j.omtn.2019.05.015. Epub 2019 Jun 4.
The role of G-quadruplex structures of LIGS-generated aptamers R1. 2 and R1. 3 in IgM specific recognition
/0 Comments/in Journals, Publications /by malli-adminFederica Moccia,Chiara Platella, Domenica Musumeci, Sana Batool, , Hasan Zumrut, John Bradshaw, Prabodhika Mallikaratchy*, Daniela Montesarchio* “The role of G-quadruplex structures of LIGS-generated aptamers R1. 2 and R1. 3 in IgM specific recognition” : Int J Biol Macromol. 2019 Apr 22; 133:839-849. doi:10.1016/j.ijbiomac.2019.04.141; 2019.
Ligand-guided-selection method for screening antigen-specific ligands
/0 Comments/in Journals, Publications /by malli-adminSynthesis of stable azide and alkyne functionalized phosphoramidite nucleosides
/0 Comments/in Journals, Publications /by malli-adminDimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells
/0 Comments/in Journals, Publications /by malli-adminSana Batool, Kimon V Argyropoulos, Roksana Azad, Precious Okeoma, Hasan Zumrut, Sanam Bhandari, Rigzin Dekhang, Prabodhika Mallikaratchy* ” Dimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells “Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (1), 232-240. doi:10.1016/j.bbagen.2018.10.006. Epub 2018 Oct 17.